Multifunctional microcapsules for islets entrapment
Multifunctional microcapsules for islets entrapment
We introduced a new approach for the integrated immunoprotection of transplanted islets, irrespective of the islet origin and maturation level. We designed microcapsules, based on alginate coated with polyornithine, but containing multiple compartments that can interact with the encapsulated cell. In this approach, the ‘‘islet compartment’’ benefit from a ‘‘chemical/pharmacologic agent compartment’’ constituted of a sustained release formulation able to deliver the included biological response modifiers for long periods of time.
PUBLICATIONS..
Multifunctional microcapsules for pancreatic islet cell entrapment: design, preparation and in vitro characterization.
Giovanni Luca, Giuseppe Basta, Riccardo Calafiore, Carlo Rossi, Stefano Giovagnoli, Elisabetta Esposito, Claudio Nastruzzi.


Round robin experiment “Bead production technologies.
Claudio Nastruzzi, Luca Bilancetti, Marek Bucko, Branko Bugarski, Jozef Bukowski, Peter Gemeiner, Dorota Lewinska, Verica Manojlovic, Benjamin Massart, Viktor Nedovic, Denis Poncelet, Ulf Pruesse, Stefan Rosinski, Swen Siebenhaar, Lucien Tobler, Alica Vikartovska, Klaus-Dieter Vorlop.


Microcapsules of pectine & alginate for cell entraptment

COST 840 STSM.
In the Laboratoire de Biotechnologie Chimique (LBCh) Institut des Sciences et Ingénierie Chimiques (ISIC) Facultè des Sciences de Base (SB) Ecole Polytechnique Fédérale de Lausanne (EPFL)
Luca Bilancetti.
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l. UNIVERSITY of FERRARA. l. FACULTY of PHARMACY. l. COST865. l. CONTACT US. l